Rejuran aftercare is just as important as the treatment itself. The way you look after your skin in the hours and days following your appointment has a direct impact on how quickly you heal, how comfortable you feel, and how good your final results look. This guide walks you through exactly what to do (and what to avoid) after a Rejuran treatment so you can get the most from your sessions.
Why Rejuran Aftercare Matters
Rejuran works by delivering polynucleotides (PN) derived from purified salmon DNA into the skin, where they stimulate repair, boost collagen, and improve elasticity. Because the treatment involves micro-injections, your skin needs a short recovery window to settle. Good aftercare protects those injection points, reduces the risk of irritation, and helps the polynucleotides do their job. If you are new to the treatment, our overview of what Rejuran is explains how the science works in more detail.
What to Expect Immediately After Treatment
It is completely normal to notice small raised bumps, mild redness, slight swelling, or minor bruising at the injection sites. These reactions usually settle within a few days. The small lumps in particular tend to resolve quickly, and you can read more about the typical timeline in our guide on how long Rejuran bumps last. If you want to understand the broader recovery picture, our article on Rejuran side effects covers what is normal and what is not.
Rejuran Aftercare: The First 24 Hours
The first day is the most important for protecting your skin while it begins to heal. During this window, keep things gentle and minimal:
- Leave the area alone. Avoid touching, rubbing, or massaging the treated skin unless your practitioner has advised otherwise.
- Keep skin clean. Cleanse gently with lukewarm water and a mild, non-abrasive cleanser. Pat dry rather than rubbing.
- Skip makeup. Avoid applying foundation or concealer over the injection points for at least 12 to 24 hours to lower the risk of irritation.
- Avoid heat. Stay away from saunas, hot showers, steam rooms, and intense workouts that raise your body temperature and increase swelling.
- Stay upright. Try not to lie face down for several hours to reduce pressure on treated areas.
Rejuran Aftercare: The First Week
As your skin settles over the following days, the focus shifts to gentle hydration and sun protection:
- Hydrate well. Use a simple, fragrance-free moisturiser to support your skin barrier.
- Protect from the sun. Apply a broad-spectrum SPF 30 or higher every day and limit direct sun exposure.
- Pause active ingredients. Hold off on retinoids, exfoliating acids (AHAs/BHAs), and vitamin C for a few days, or as directed by your practitioner.
- Avoid other facial treatments. Postpone facials, peels, and laser sessions for at least one to two weeks.
- Drink plenty of water. Good internal hydration supports the skin renewal process.
What to Avoid After Rejuran
To protect your results, avoid alcohol and blood-thinning supplements for 24 to 48 hours (these can worsen bruising), strenuous exercise for the first day or two, picking at any bumps or scabs, and excessive heat or UV exposure. Following these simple rules helps your skin heal evenly and keeps your results looking their best.
How Aftercare Affects Your Results
Rejuran results build gradually as collagen production increases over the weeks following treatment. Consistent aftercare supports this process. To understand when you will start to see changes, see our guide on how soon Rejuran works, and for the bigger picture on longevity, read how long Rejuran lasts. Most people need a course of treatments, which we cover in how many Rejuran sessions are needed.
When to Contact Your Practitioner
Mild redness, swelling, and small bumps are expected. However, you should contact your practitioner if you experience severe or spreading pain, signs of infection such as heat, pus, or fever, prolonged swelling that does not improve, or any reaction that worries you. If you are unsure whether the treatment is suitable for you in the first place, our article on who should not use Rejuran is a helpful starting point.
Frequently Asked Questions About Rejuran Aftercare
How long does it take to recover from Rejuran?
Most people recover within three to five days. Redness and small bumps typically fade within the first few days, while any minor bruising may take up to a week to disappear.
Can I wear makeup after Rejuran?
It is best to avoid makeup for at least 12 to 24 hours so the injection points can close and settle. After that, gentle mineral makeup is usually fine.
When can I exercise after Rejuran?
Avoid intense exercise, saunas, and anything that raises your body temperature for the first 24 to 48 hours, as heat can increase swelling and redness.
What should I not use on my skin after Rejuran?
Pause strong actives such as retinoids, exfoliating acids, and vitamin C for a few days. Stick to gentle cleansing, hydration, and daily SPF until your skin has fully settled.
Final Thoughts
Rejuran aftercare comes down to keeping things gentle, protecting your skin from heat and sun, and giving the polynucleotides time to work. With the right routine, you support faster healing and smoother, more radiant results. Explore our full range of authentic Rejuran products to plan your next steps with confidence.